This has practical applications in that a predicted tlc can be estimated from predicted fvc vc but is dependent on how well the predicted fvc fits the patient age height ethnicity etc as well as the assumption that rv tlc ratio is solely a function of age. However did make new observations about the association between the rv tlc ratio and duration of asthma. While an increase in rv tlc may be one of the first signs of chronic obstructive pulmonary disease copd and as previously stated an increase in the ratio may just be a function of age.
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